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9 Calpol Alternative Products For Children

9 Calpol Aleternative Products For Children

Calpol is probably the most well-known brand of paracetamol in liquid form for infants, toddlers, and children. Calpol range of paracetamol liquid includes Calpol Infant and Calpol 6+.

Today I will list Calpol alternative products, including other brands and forms of liquid paracetamol and alternative drugs. Although the intention is to find Calpol alternative products for toddlers and children, I included a few products, which have a minimum age restriction of 12 years and above.

Firstly, however, I will review the composition of Calpol Infant and Calpol Six Plus to identify how much paracetamol (the main active ingredient) is present in each product.

What Is Calpol?

Calpol is a branded version of Paracetamol, which comes in the form of a liquid for infants, toddlers, and children. Paracetamol is used in the treatment of mild to moderate pain (for example, headache, tooth pain, sore throat) and also as antipyretic medication to reduce fever (temperature).

Broadly speaking, Calpol paracetamol is available in two forms:

  • Calpol Infant (with sugar and sugar-free version)
  • Calpol Six Plus (with sugar and sugar-free version)

Both the above products also come in two different sizes – 100ml and 200ml bottles and different flavors. 100ml bottle of Calpol is licensed as general sale medicine (GSL) meaning it is available for self-selection by customers in stores and pharmacies.

A larger 200ml bottle of Calpol suspension is a pharmacy-only product (P). P products are sold from behind a pharmacy counter and online chemists.

Quick FAQ

Does Calpol make children sleepy?
Calpol does not make children sleepy. The idea that Calpol makes children sleepy is a misbelief.

Summary of Calpol paracetamol availability:

Availability Paracetamol content Flavour
Calpol Infant 100ml GSL 120mg in 5ml Strawberry
Calpol Infant sugar-free 100ml GSL 120mg in 5ml Strawberry
Calpol Infant 200ml P 120mg in 5ml Strawberry
Calpol Infant sugar-free 200ml P 120mg in 5ml Strawberry
Calpol 6+ sugar-free 80ml GSL 250mg in 5ml Strawberry
Calpol 6+ 200ml P 250mg in 5ml Orange & strawberry
Calpol 6+ sugar-free 200ml P 250mg in 5ml Strawberry

GSL: general sale listing item, available in supermarkets, pharmacies for customer self-selection
P: medicines: which are sold from behind a pharmacy counter and online pharmacies.

Calpol Active Ingredients And Age Restrictions

Calpol Infant and Calpol 6+ contain paracetamol as an active ingredient.

Calpol age Restictions

  • Calpol Infant can be given to babies aged two months to six years (baby weight needs to be over 4kg, and the baby was born after 37 weeks).
  • Calpol 6+ can be given to children over six years of age.

How much paracetamol do you get in Calpol?

  • Calpol Infant contains 120mg of paracetamol per 5ml of suspension.
  • Calpol 6+ contains 250mg of paracetamol per 5 ml of suspension.

Calpol Alternative Products

There are plenty of paracetamol products for infants, toddlers, and children. Most supermarkets and pharmacy chains sell their brands of paracetamol suspension for infants and children. Calpol alternative products include:

1. Calpol alternative – Tesco’s Children paracetamol

Tesco’s children’s paracetamol is one of the cheapest options when it comes to liquid paracetamol for children and toddlers.

Smaller bottles of Tesco’s children’s paracetamol 100ml bottles are kept on the shop floor, whereas bigger 200ml bottles are kept behind the pharmacy counter. Tesco’s range of paracetamol for babies, toddlers, and children comes in two options:

Tesco Children’s Paracetamol 2 Month Plus:

  • 120mg of paracetamol per 5ml of syrup
  • Cherry flavor
  • Sugar-free
  • Colour free

Tesco Children’s Paracetamol Six Plus:

  • Contains 250mg/5ml of paracetamol
  • Orange flavor

 2. Boots children’s paracetamol

Quick FAQ

Is Calpol as strong as paracetamol?
Calpol Infant contains 120mg of paracetamol in each 5ml, whereas Calpol Six Plus 250mg of paracetamol in every 5 ml. Both products are equally strong as 'paracetamol' and other paracetamol-containing products for relevant age groups.

Boot’s brand of children’s paracetamol is another Calpol alternative. It comes in two different forms:
Boots paracetamol oral suspension TWO months plus:

  • Contains 120mg/5ml of paracetamol
  • Strawberry flavor
  • Sugar-free

Boots paracetamol oral suspension SIX years plus:

  • Contains 250mg/5ml of paracetamol
  • Strawberry flavor
  • Sugar-free

Both products also offer great value for money.

All other pharmacy chains and supermarkets including Lloyds Pharmacy, Morrisons, Sainsbury’s sell similar paracetamol products, with the same licensed use – TWO months plus or SIX months plus.

I will now move away from Calpol alternative paracetamol suspension to other alternatives. As we experienced during the first lockdown, all children’s paracetamol suspensions, including Calpol, were out of stock.

Quick FAQ

Is paracetamol and Calpol the same?
Calpol is a branded version of paracetamol, therefore it's the same medication as paracetamol. There are several alternatives on the market that contain the same dose of paracetamol.

What is the choice for other Calpol alternative medicines?

3. Paracetamol suppositories as Calpol alternative

Alvedon - paracetamol suppositories as alternative to paracetamol liquid for children

Paracetamol suppositories come in three different strengths and broadly speaking can be used by babies, toddlers, and children from 2 months up to 12 years of age.

Paracetamol suppositories are not commonly prescribed or sold mainly due to the high cost of this form of paracetamol. In the UK children’s paracetamol suppositories are sold under the brand name Alvedon.

Alvedon suppositories come in the following strengths:

Name Paracetamol content / suppository Licensed age
Alvedon Suppositories 60 mg 60mg of paracetamol Up to 1 year
Alvedon Suppositories 125 mg 125mg of paracetamol 1-5 years
Alvedon Suppositories 250 mg 250mg od paracetamol 6-12 years

Where can you buy paracetamol suppositories?

Paracetamol suppositories are pharmacy-only medicines (P). P products can only be purchased from pharmacies, including online chemists. Since paracetamol suppositories are not commonly prescribed and requested by customers, most pharmacies do not stock this form of paracetamol.

However, like other P medicines or drugs, paracetamol suppositories can be ordered on an individual basis, when a request is made by customers, for the same or next-day delivery from leading pharmaceutical distributors.

How much do Paracetamol suppositories cost?

  • Alvedon Suppositories 60 mg (pack size: 10): £11.95 (Pharmacy price: £20.32)
  • Alvedon Suppositories 125 mg (pack size: 10): £13.80 (Pharmacy price: £23.46)
  • Alvedon Suppositories 250 mg (pack size: 10): £27.60 (Pharmacy price: £46.92)

The above prices are trade prices. When purchasing a product from a pharmacy, one is expected to pay 50%-70% on top of the trade price. Overall the price of paracetamol suppositories makes this form too expensive to individual patients as well as to be prescribed on the NHS.

4. Kool ‘N’ Soothe Kids Cooling Strip

Kool ‘N’ Soothe Kids Cooling Strip is a non-medicated sheet, which can be used by children over 1 year of age. Kool ‘N’ Soothe Kids Cooling Strip is placed on the forehead, giving an instant cooling sensation for up to 8 hours.

This product has overall amazing reviews on Amazon.co.uk. It has to be remembered that  Kool ‘N’ Soothe Kids Cooling Strips are non-medicated, which means they are unlikely to reduce fever (temperature), however ‘the cooling’ sensation will make a child more comfortable during their illness.

Kool ‘N’ Soothe Kids Cooling Strips can be used alongside other medicines.

5. Soluble Paracetamol as Calpol alternative

Soluble paracetamol is another less commonly used form of paracetamol. Some pharmacies and supermarket may sell soluble paracetamol; for example, Tesco sells Neolab brand of Soluble Paracetamol.

Each soluble tablet of paracetamol usually contains 500mg of paracetamol. Licensed age may differ between products; for example, Neolab brand of Soluble Paracetamol is licensed for children ten years of age and over.

Soluble paracetamol is combined very often with caffeine, for example, Panadol Extra (age restrictions – 12 years and above).

Can I give soluble Paracetamol to a toddler?

Theoretically, it is possible to give soluble Paracetamol to a toddler; however, this would be unlicensed use of this medication. A doctor can prescribe medicines outside of the product license.

How would it work?

As an example, a recommended dose for children aged 6-8 is 250mg of Paracetamol four times a day (in 24 hours). In order to get this dose from 500mg Paracetamol, it would be necessary to dissolve one tablet in a certain amount of water.

To make it simple: 10ml of water. Since we are dissolving 500mg of Paracetamol in 10ml of water, half of it (5ml) would contain 250mg of Paracetamol.

6. Ibuprofen as Calpol alternative

Ibuprofen as Calpol alternative

Ibuprofen belongs to a group of drugs called Non-Steroidal Anti-inflammatory Drugs (NSAIDs).

Like Paracetamol, Ibuprofen is also used to help manage the pain and to reduce fever (temperature).

Additionally, Ibuprofen can be used as an anti-inflammatory drug. Both Paracetamol and Ibuprofen have similar use. Ibuprofen liquid is licensed for babies, toddlers, and children from 3 months of age.

Ibuprofen: Restrictions on use

Ibuprofen has more restrictions on the use as compared to Paracetamol, for example:

  • Ibuprofen should not be given to children with chickenpox
  • Ibuprofen should not be given to children who had previous hypersensitivity reactions (for instance asthmatic patients)
  • Ibuprofen should not be given to patients with a history of ulcers

For more information, read the product information leaflet or speak to the pharmacist.

Similar to Paracetamol alternatives, Ibuprofen is sold under different brand names. Nurofen is the best-known brand of Ibuprofen. Most supermarkets and pharmacies sell their brands of Ibuprofen liquid for toddlers and children.

Ibuprofen comes in different forms, which can be considered as an alternative to liquid preparations, for example, Ibuprofen melts.

7. Ibuprofen Melts

Ibuprofen melts contain 200mg of Ibuprofen per tablet. Ibuprofen melts are placed on the tongue and allowed to dissolve with no need for water. Ibuprofen melts can be used by adults and children over 12 years of age.

8. Paracetamol tablets as Calpol alternative

Standard paracetamol tablet sold in pharmacies and supermarket contains 500mg of paracetamol. Paracetamols tablets have age restrictions on use. Usually, Paracetamol tablets can be given to children ten years of age and above.

Can you give Paracetamol tablets to children under ten years?

The above scenario is similar to the earlier discussed use of soluble paracetamol outside of its license. Again, in theory, it would be possible to use a lower dose by cutting one paracetamol tablet in half. Each half would contain 250mg of paracetamol, which could potentially be used in children under ten years of age.

9. Co-codamol (Paracetamol & Codeine)

Co-codamol (a combination of Paracetamol with Codeine) is included as the last alternative to Paracetamol liquid because it is licensed for adults and children over 12 years of age.

Additionally, this combination drug is recommended (licensed) for pain relief, for example, migraines, toothache only when it is not relieved by other analgesics such as paracetamol or Ibuprofen (alone).

Taking Codeine/Co-codamol is usually associated with side effects, some of which may include:

  • Drowsiness/sedation (feeling sleepy)
  • Nausea (feeling sick)
  • Constipation

Co-codamol is a pharmacy-only medication that is available in the form of tablets, capsules, and dissolvable tablets. Co-codamol may not provide the best pain relief as compared to other analgesics.

Can You Use Paracetamol ‘SIX plus’ Instead Of Paracetamol ‘INFANT’?

This was a common question asked during COVID lockdown 1 when in the first instance infant Paracetamol went out of stock. It is possible to adjust the dose (volume taken) for Paracetamol SIX plus to match the equivalent dose for children below six years of age.

Use of Paracetamol ‘six-plus’ in children under six years of age would be unlicensed use.
Likewise, it would be possible to use infant Paracetamol in children who are six years of age and above by adjusting the dose (volume taken) of Paracetamol.

Can You Alternate Calpol With Nurofen?

I want to finish this post by discussing the alternate use of Calpol (paracetamol) with Nurofen (ibuprofen), which sometimes may be recommended.

The advice on taking Paracetamol and Ibuprofen at the same time differs and depends on the age:

  • For adults and children over 16 years of age, it is possible to take paracetamol and ibuprofen at the same time.
  • For children below the age of 16: NHS does not recommend giving Paracetamol and Ibuprofen together at the same time unless recommended by a healthcare professional. Parents can try the second medication instead if, for example, a child is still in ‘distress’ after giving them a dose of Paracetamol. A dose of Ibuprofen could be given before the next dose of Paracetamol. Both drugs should not be given routinely alternately.

Why giving paracetamol and ibuprofen at the same time to a child is not recommended?

NHS recommendation comes from NICE guidelines on the management of fever under 5s. NICE guidelines used a systemic review (comparison of different studies) which assessed the safety and efficacy of Paracetamol and Ibuprofen use at the same time.

Few clinical studies showed that both dual and alternating dosage might be more effective in reducing children’s fever compared to the use of a single drug alone.

These studies did not include the ages of children. The use of a single analgesic was recommended, as insufficient information exists to recommend the use of both drugs at the same time. No serious side effects were reported in any of the included studies (NICE, 2013).


Customers have a good choice of Calpol alternative Paracetamol products with many oral suspensions available in most supermarkets and pharmacies. Most supermarket brands are cheaper than Calpol paracetamol, however, one aspect that needs to be considered is the taste of medicine.

Some children may find Calpol products more acceptable than other paracetamol suspensions. In a scenario where parents struggle to find children’s paracetamol, other drugs may be considered, as reviewed in this post.



NICE (2013). NICE guideline NG143.c Available at https://www.nice.org.uk/donotdo/when-using-paracetamol-or-ibuprofen-in-children-with-fever-do-not-give-both-agents-simultaneously Accessed on 10/11/2020

Oncel, M.Y., Yurttutan, S., Uras, N., Altug, N., Ozdemir, R., Ekmen, S., Erdeve, O. and Dilmen, U., 2013. An alternative drug (paracetamol) in the management of patent ductus arteriosus in ibuprofen-resistant or contraindicated preterm infants. Archives of Disease in Childhood-Fetal and Neonatal Edition98(1), pp.F94-F94. Available at https://fn.bmj.com/content/98/1/F94.extract Accessed on 10/11/2020