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Chloramphenicol Eye Drops To Treat Infections Of The Eye

chloramphenicol eye drops

Approximately 6 million people in the US per year are affected by acute conjunctivitis, a bacterial infection in the eye. The cost to treat it is about 377USD to 857USD per year. Eye drops are widespread and widely used in the US, especially for bacterial infections. Chloramphenicol is one such antibacterial eye drop.

Chloramphenicol belongs to a class of drugs called antibiotics. Popular brand names under which the medication is sold are Chloromycetin, Optrex Infected Eye Drops, and Optrex Infected Eye Ointment. Chloramphenicol comes in Capsules, Injections, Oral liquid, Eye ointment, and Eye drops. Chloramphenicol comes in the strength of Chloramphenicol 0.5% w/v and Chloramphenicol 1% w/v.

How Does Chloramphenicol Work?

By attaching to the bacterial ribosome and decreasing protein synthesis, Chloramphenicol prevents bacterial growth.

Because Chloramphenicol is lipid-soluble, it can pass through bacterial cell membranes. It then reversibly binds to the L-16 protein of the 50S subunit of bacterial ribosomes, limiting peptide bond formation and subsequent protein synthesis by preventing amino acid transfer and increasing peptide chains (perhaps by suppressing peptidyl transferase activity).

Who Can Use It And Who Cannot?

Most adults and children can use Chloramphenicol. Children under the age of two years need a prescription from a doctor.

People suffering from bacterial eye infections can use this medicine. Chloramphenicol does not work on other types of eye infections besides bacterial ones.

Chloramphenicol is not suitable for some people. People who have an allergic reaction to Chloramphenicol should avoid using this. People suffering from a rare illness known as aplastic anemia cannot use this medicine in its oral form.

Some people who have sensitive eyes may find it hard to use this eye drop and consult a doctor before using it. It is also not advised to use for other reasons besides bacterial eye infection.

How To Use It?

Before using eye drops, make sure your hands are clean. Please do not touch the dropper tip or allow it to come into contact with your eye or any other surface to avoid infection.

Wearing contact lenses while dropping this medication is not recommended. Contact lenses should be sterilized according to the manufacturer’s instructions, and you should see your doctor before using them again. To make a pouch:

  • Tilt your head back, gaze upward, and draw down the lower eyelid.
  • Place one drop into the pouch with the dropper directly over your eye, generally 2 to 6 times daily or as advised by your doctor.
  • For 1 to 2 minutes, look downward and softly close your eyes.
  • Apply moderate pressure to the corner of your eye (near the nose) with one finger to keep the medicine from leaking out.
  • Avoid blinking and rubbing your eyes. If your dosage isn’t working, repeat these instructions.

We suggest you regularly use this medication to get the most benefit from it.

Study On Its Effectiveness

The Department of Ophthalmology at Kinki School of Medicine, located in Osaka, Japan, conducted a study on the efficacy of Chloramphenicol eye drops.

They looked at how effective chloramphenicol eye drops were in treating MRSA(Methicillin-resistant Staphylococcus aureus) conjunctivitis. They also looked for MRSA and MR-CNS in the skin and conjunctiva of atopic dermatitis patients’ lids.

Chloramphenicol eye drops had an 81 percent effectiveness rate in treating MRSA conjunctivitis. S. aureus was the most common species in the conjunctival sacs of atopic dermatitis (48 percent), with MRSA accounting for 18 percent.

Quick FAQ

Is it ok to use chloramphenicol eye drops after 28 days?
Protect the medicine from the sun. After opening the tube, do not take this drug for more than 28 days. After this period, the eye ointment left in the tube should be returned to your pharmacist.

Chloramphenicol Dosage

It is suggested to give two drops to the affected eye every three hours for adults and children. Only to be used during the day. After the eye seems normal, treatment should be continued for at least 48 hours.

Follow the instructions prescribed by your doctor and consult them if you are confused.

Chloramphenicol Side Effects

Side effects are rare and do not occur to most people. However, if any cases or symptoms of any side effects, consult your doctor immediately.

Some side effects caused by Chloramphenicol eye drops are:

  • Temporary blurred vision
  • Stinging sensation in the eye
  • Burning in the eye
  • Red eyes

These symptoms may last only for a short while. Do not operate machinery until your eyes feel normal and not blurred.

Quick FAQ

Can Chloramphenicol make the eye worse?
It can cause temporary blurred vision, redness, burning, and stinging.

Drug Interactions

Chloramphenicol Eye drops do not cause any severe interactions with other drugs. However, it would be best not to use eye drops right after applying any eye ointment.


Overusing the Chloramphenicol eye drops can cause eye redness and irritation to the eye. We suggest you strictly follow the dosage as directed by your doctor.

This eye drop is only used to treat bacterial infection in the eye and not for other reasons.

What are the Alternative Eye Drops For Chloramphenicol?

Like Chloramphenicol, there are a few other drugs/ eye drops to treat bacterial infection.

They are listed below:

  • Polymyxin B
  • Trimethoprim eye drops
  • Neomycin (Maxitrol)
  • Gentamicin eye drops
  • Doxycyclin
  • Bacitracin
  • Azithromycin
  • Cipro or Ciprofloxacin

Quick FAQ

Which is the best antibiotic for an eye infection?
Oral antibiotics such as azithromycin or doxycycline are effective treatments for an eye infection.

How To Get Chloramphenicol Eye Drops Online?

The chloramphenicol eye drop is perhaps the first choice of antibiotic, especially to treat conjunctivitis. It is available without a prescription and can be purchased over the counter or from online pharmacies.

Customers can purchase an antibiotic eye drop like Chloramphenicol through a private service offered by several online pharmacies. Patients are often asked to complete an online questionnaire, which is then assessed by a healthcare doctor, who issues the prescription and delivers the product to the patient. The cost of an antibiotic eye drop is usually included in the purchase; however, this varies per pharmacy.


Chloramphenicol Eye Drop is an antibiotic eye drop that treats bacterial infections in your eyes. Always follow the guidelines mentioned on the information leaflet or as directed by your healthcare doctor. This medication is available without a prescription at local stores or online pharmacies. For any side effects, consult your healthcare doctor right away.