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Flibanserin (Addyin) In The UK

Flibanserin (Addyin) In The UK

In this post, we will be looking at FDA Approved pills to increase sex drive in females. Flibanserin (Addyin) drug with an emphasis on the effectiveness of the treatment and its availability in the UK.

Flibanserin, available under the branded name of Addyi, is FDA approved (USA) drug for the treatment of premenopausal women (women who have not gone through menopause) with hypoactive (low) sexual desire disorder (HSDD).

Flibanserin (Addyin) has been wrongly named as ‘pink Viagra’ after a drug used for erectile dysfunction in men, Viagra (Aronix-sildenafil). More about this in one of the further paragraphs.

What Is Hypoactive (low) Sexual Desire Disorder (HSDD)?

HSDD I is characterized by a low or absent interest in sexual activity (‘low libido’). There is no UK guide or official information on HSDD and its diagnosis. Some of the following symptoms may be experienced by women with HSDD (Meston & Stanton, ND):

  • Absent or reduced interest in sexual activity
  • Absent or reduced sexual thoughts or fantasies
  • No or reduced initiation of sexual activity
  • Lack of response to a partner’s attempts to initiate
  • Absent or reduced sexual excitement or pleasure in most or all sexual encounters (e.g., regardless of partner)

Addyi.com provides a simple questionnaire that may help with the diagnosis of HSDD.

Numbers of factors contribute to HSDD, including psychological and physical. The imbalance of chemicals in the areas of the brain responsible for the sexual drive may also be responsible for symptoms of HSDD.

Take a look at this video to understand what the manufacturers claim.

Quick FAQ

How long does it take to show effects?
After the consumption, it may take about 2-4 weeks to show positive effects.

Flibanserin (Addyi) Indications Of Use


As described above, Flibanserin (Addyi) is licensed for premenopausal women who experience low sexual desire that causes distress and interpersonal difficulties.

This indication does not include similar symptoms caused by (FDA, 2015)

  • Medical condition or being diagnosed with a psychiatric condition
  •  Use of medication
  • Relationship problems

Addyi is not used to enhance sexual performance.

It is thought that Flibanserin controls serotonin and dopamine activity in certain parts of the brain, improving their balance, and therefore is responsible for the regulation of sexual response (Allers et al., 2010).

Quick FAQ

Can you have alcohol with Addyi?
Although the FDA is still worried about Addyi's connection with alcohol, people with HSDD do not have to abstain from alcohol entirely when taking this drug. So, in short, you can drink alcoholic beverages with Addyi.

Is Flibanserin (Addyi) Available In The UK? Is It Available On NHS?

Flibanserin (Addyi) is not available in the UK. If Flibanserin becomes available in the UK, it would be available to a limited number of patients due to the high cost of this medication. Almost certainly, it would not be available on NHS due to the cost-benefit ratio.

Is Flibanserin (Addyi) Effective?

In 2010 Flibanserin (Addyi) failed to get a license due to an inadequate risk-benefit ratio, mainly due to concerns about side effects associated with the treatment. Five years later, and with additional information from further studies FDA approved Addyi.

A systemic review on Efficacy and Safety of Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Women analyzed information from five published and three unpublished studies, including 5914 women.

Key findings from a systemic review on the effectiveness of Addyi (Jaspers et al., 2016):

  • On average, women who were treated with Flibanserin experienced one-half additional satisfying sexual events per month
  • Treatment with Flibanserin was associated with statistically and clinically significant increased risk of side effects, including the risk of dizziness, somnolence, nausea, and fatigue. In other words, the clinical benefits of the treatment are marginal, with a significant risk of side effects.
  • The quality of outcome evidence from studies was graded as low by two independent researchers (Cochrane Collaboration)

Quick FAQ

Does Addyi work instantly?
Flibanserin usually begins to have beneficial effects two to four weeks after a woman starts taking it. Stop taking Addyi if you don't notice a difference after two or three months.
Does Flibanserin cause weight gain?
Clinical trials looked into this question in particular. Flibanserin did not cause patients to gain weight in the long run. In fact, there was a weight-loss tendency.

Flibanserin (Addyi) Cost

Flibanserin (Addyi) cost

The cost of Addyi in the USA for 30 days' supply is around $426 (£331).

When covered by insurance in the USA, the cost is around $25 / month (Addyi.com, ND).

Why Flibanserin (Addyi) Is Not A ‘Pink Viagra’

As we discussed in one of the above subtopics, Addyi affects changes in specific brain parts. In contrast, the mechanism of action of Viagra (sildenafil), a drug used to treat erectile dysfunction in men, works in a completely different way.

Sildenafil’s mode of action involves smooth muscle relaxation, which causes vasodilation and increases blood inflow into the penis. Sildenafil does not have any activities on the brain.

To sum up, the evidence behind the effectiveness of Flibanserin (Addyi) is of low quality. Flibanserin (Addyi) is not available in the UK, and it is unlikely we will see it being prescribed in the UK.

Quick FAQ

Is Flibanserin an OTC medication?
Flibanserin is not an OTC drug. It would help if you had a valid prescription to get Flibanserin.
Can Flibaserin be taken by men?
Men should not take Flibanserin as it is medicine only to be used by women.