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Is Modafinil The Right Choice For Sleep Apnea?

Is modafinil the right choice for sleep apnea

Sleep is a luxury money can’t buy. This quote holds quite true. When it comes to sleep, we need the best luxuries to get that healthy sleep. But, there are various disorders that can affect you and your health which can cause big troubles during sleep. Let’s address all such disorders today to help you get that comfortable sleep and good night.

There are many problems and disorders which can cause trouble in your sleep like

  • Hypersomnia – Excessive sleepiness
  • Insomnia – Lack of sleep
  • Chronic Delayed Sleep Syndrome – Late night sleep
  • Circadian Rhythm Sleep Disorder
  • Mental health issues like anxiety and depression

And last but not the least, SLEEP APNEA
All are easy to deal with but difficult to cure. One problem that needs special attention among these is – SLEEP APNEA. With this article on sleep apnea, read on and stay glued till the end to know an eye-opener fact and health advice on how to use “Modafinil Drug for Sleep Apnea”- the right way and right choice of treatment.

It is a known fact that a good amount of sleep and quality of sleep benefits the heart, weight, mind, and body. It helps to activate the whole system. However, unhealthy eating habits and lack of physical activity are factors that can interfere with sleep. The problem many people suffer from is obstructive sleep apnea (OSA).

Sleep Apnea

sleep apnea

The word apnea means not breathing.
The upper airway is kept open by the tone of the muscles that make up the walls of the airway. During deep sleep, the muscles reduce their tone, and the upper airway narrows.
A slight narrowing causes snoring, more narrowing causes hypopnea (“short breathing”), while complete obstruction causes apnea

If the blockage lasts long enough, the oxygen level in the person’s blood drops.
This episode ends when the person’s sleep lightens from a state of deep sleep or breaks up completely (“attentive”).

Risk factors for sleep apnea 

  • Obesity
  • Structural abnormalities in the upper airway
  • Family history of sleep apnea
  • Hormone disorders such as hypothyroidism and polycystic ovary syndrome
  • Smoking and alcohol abuse.

Symptoms of sleep apnea

Symptoms of sleep apnea

Symptoms of sleep apnea can be classified into night-time and daytime symptoms.

Night-time symptoms include heavy snoring, apnea (breathing lasting 10 seconds or longer), being seen by a sleeping partner in bed, choking, frequent urination, sweating, Erectile dysfunction, acid reflux, and sleeplessness.

Daytime symptoms include excessive daytime sleepiness, difficulty concentrating, memory loss, irritability, fatigue, and depression.

Diagnosis of sleep apnea: Adults who have symptoms of sleep apnea can test themselves using a questionnaire that is familiarly known by the STOP-BANG. Stopbang refers to

S- Snoring

T– Tired

O-Observable apnea

P- Blood pressure

B- BMI (Body Mass Index – Weight in Kilograms (Height in Meters) 2) > 35 kg/m2

A-Age > 50 years

N-Neck circumference >16 inches and

G-Gender Male

Those who score 3 or higher on this questionnaire should see a sleep medicine specialist and undergo a sleep study.

Treat for Sleep Apnea – The Right Choice Modafinil  |

what is modafinil

What is Modafinil?

  • Modafinil is a wakefulness-promoting drug used in the treatment of excessive sleepiness due to Narcolepsy (chronic sleep disorder)
  • Shift work sleep disorder
  • Idiopathic hypersomnia
  • Excessive daytime sleepiness
  • And above all which is an important point to discuss, Obstructive sleep apnea (breathing during sleep starts and stops).
  • Modafinil is a drug used to reduce sleepiness in patients with sleep disorders such as narcolepsy.
  • Usually can be used for people who feel sleepy during abnormal hours due to an unpredictable lifestyle. It is also known for its sedation-increasing abilities.
  • It should not be used to forcefully wake a person with no sleep disorder

How does Modafinil work?

This medication is used in sleeping disorders like narcolepsy, etc. to prevent excessive sleepiness. It does this indirectly by stimulating the release of orexin neuropeptides and histamine, which cause wakefulness.

Modafinil Uses

Modafinil is used for the treatment of:

  • Narcolepsy
  • Sleep apnea
  • Fatigue
  • Snoring
  • Lethargy

What are the side effects of Modafinil?

Some common side effects that may occur after taking modafinil are:

  • Dizziness
  • Headache
  • Nervousness
  • Nausea
  • Difficulty sleeping

The following types of side effects may occur, but do not always occur-

If symptoms persist, please consult a physician.

  • Mood changes
  • Headache
  • Abdominal pain
  • Constipation
  • Diarrhoea
  • Dizziness
  • Chest pain
  • Increased heart rate
  • Loss of appetite
  • Nervousness
  • Anxiety
  • Depression
  • Insomnia
  • High blood Pressure
  • Excessive Thirst, Dry Mouth

What are the contra-indications of Modafinil?

  • Hypersensitivity or allergies
  • Pain in chest
  • Irregular heartbeat or racing pulse
  • Liver problems and kidney problems
  • Hypertension
  • Alcohol abuse
  • Psychosis and mania

Is there any scope for a substitute?

When it comes to finding a Modafinil alternative, there is not much choice out there. This is because of how well the drug works to prevent extreme sleepiness. The composition of the drug is such that Modafinil falls under the category of the best wakefulness promoting agents, and why many people wonder how to get modafinil online and at good prices.

Modafinil is recognized as a smart drug

Modafinil is very famous among the youth. They recognize it as a smart drug.Doctors recommend the use of this medicine to people suffering from sleep problems
Precautions related to the use of modafinil

  • Do not give to children under 18 age
  • Do not consume alcohol with it
  • Limit caffeine intake
  • Do not stop taking the medicine suddenly, as it can cause problems
  • Do not take the medicine at all if you are allergic to the medicine or any of its other ingredients

Modafinil Dosage & How to Take – Modafinil

This is the usual dose to be administered for the most common treatment cases. Please note that each person and their case is different, so the dose may vary depending on the disease, the method of drug administration, the patient’s age, and medical history.

dose of medicine
Know the dose of medicine according to

    • Disease
    • Age group
    • Dosage

Adult 

Disease: Sleep apnea

After or before meals: You can take the medicine anytime preferably after meals

Maximum dose: 200 mg

Drug Type: Tablets

Medication: Oral

Frequency (how often to take the drug): 1 time

Duration of medication: NA treatment will continue for a long time

Other instructions: Dose may increase up to 400 mg/day as needed


Elderly

Disease: Sleep apnea

After or before meals: You can take the medicine anytime preferably after meals

Maximum dose: 200 mg

Drug Type: Tablets

Medication: Oral

Frequency (how often to take the drug): 1 time

Duration of medication: NA treatment will continue for a long time

Other instructions: Dose may increase up to 400 mg/day as needed


Modafinil Related Warnings 

Is Modafinil safe to consume or apply when pregnant?

Pregnant women may experience mild side effects from Modafinil. If you feel like it, stop it and start only on the advice of a doctor.

Is Modafinil safe while breastfeeding?

Breastfeeding women may experience serious side effects after taking Modafinil. It should not be taken only under medical supervision.

What is the effect of Modafinil on the kidneys?

Modafinil side effects rarely affect the kidneys

What is the effect of Modafinil on the liver?

Side effects of modafinil rarely affect the liver

What is the effect of Modafinil on the heart?

Very few cases of side effects of Modafinil on the heart have been reported.

Drug interactions 

Modafinil should not be taken with the following drugs as it causes serious side effects in patients

Serious drug interactions

  • Amoxicillin
  • Clarithromycin
  • Esomeprazole
  • Betacap TR 40 Capsule
  • Betacap 20 Tablet
  • Betacap TR 80 Capsule
  • Inderal 10 Tablet
  • Diazepam
  • Depsol Forte Tablet
  • Tancodep 2 Mg / 25 Mg Tablet
  • Calmpose 10 Mg Injection
  • Calmpose 5 Mg Tablet
  • Phenytoin
  • Epsolin 100 Tablet
  • Epsolin ER 300 Tablet
  • Ectoin 300 ER Tablet
  • Epsolin 300 Tablet

Modafinil Contra-indications

If you suffer from any of the following diseases, you should not take Modafinil unless your doctor tells you to

  • Bipolar disorder
  • Schizophrenia
  • Suicide
  • Heart disease
  • Liver disease
  • Kidney disease

FAQ’s

Is Modafinil habit-forming or addictive?
No, you do not become addicted to Modafinil.
Is it safe to drive or operate heavy machinery when it is taken?
You may feel drowsy after taking Modafinil. So it is not safe to carry out these activities.
Is it safe?
Yes, but only take Modafinil according to medical advice.
Can it treat mental illness?
No, Modafinil cannot cure any type of mental illness.

Modafinil Interactions with Food

Is it safe to take Modafinil with food?
Yes, Safe
Interactions between alcohol and modafinil
Taking alcohol and Modafinil together can have serious effects on your health.

A valuable health advice for all the readers who intend to consume ‘Modafinil’ drug

‘Modafinil’ drug + Calcium and Vitamin D supplements

THINKING WHY ? 

‘Modafinil’ drug, which removes sleep problem, is making bones weak

‘Modafinil’ drug, which removes sleep problem, is making bones weak

  • The matter came to the fore in the research of scientists of the Central Drug Research Institute
  • Doctors prescribe the drug ‘Modafinil’ to people suffering from sleep problems, but this medicine is weakening the bones.
  • This has been revealed in the research of scientists of the Central Drug Research Institute.
  • About two years ago i.e. in the year 2018, research conducted by scientists of Central Drug Research Institute (CDRI) claimed that modafinil was making bones weak.
  • During the research, scientists had found that the drug modafinil, by increasing the amount of a burning protein released by bone-building cells, causes the bones to dissolve. This research was also published in a science journal at that time.

How ‘Modafinil’ drug  dissolves bones

  • Experts say that research has found that an inflammatory (inflammatory) released from bone-building cells causes bones to rot.
  • On the basis of his experiments on animals, it is researched that due to the hyperactivity of inflammatory proteins, the bone starts to melt.
  • Before the age of 30, there is a blockage in bone strength in humans. This increases the risk of early arthritis and fractures.
  • In such a situation, a drug like modafinil can prove to be very harmful.

The craze among the youth for the use of ‘Modafinil’ drug

  • This drug is being used extensively to reduce sleepiness in youth.
  • The craze of night-outs has increased amidst the changing lifestyle in the metros.
  • The use of modafinil drugs improves concentration, learning ability, and memory.
  • Along with this, many other benefits have also been claimed to be there. Apart from this, this medicine is considered the safest. Due to this the craze for this medicine has increased. That’s why the research was done on it.

So, do not ignore your snoring which can lead to sleep apnea, and take some measures by taking the right medicine for sleep apnea – Modafinil with precautionary measures and health advice with a daily dose of calcium and vitamin D supplements.

References
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  3. Black JE, Hirshkowitz M. Modafinil for treatment of residual excessive sleepiness in nasal continuous positive airway pressure-treated obstructive sleep apnea/hypopnea syndrome. Sleep. 2005 Apr;28(4):464-71. doi: 10.1093/sleep/28.4.464. PMID: 16171291.https://pubmed.ncbi.nlm.nih.gov/16171291/ Accessed on 22/9/2021
  4. Pack AI, Black JE, Schwartz JR, Matheson JK. Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea. Am J Respir Crit Care Med. 2001 Nov 1;164(9):1675-81. doi: 10.1164/ajrccm.164.9.2103032. PMID: 11719309. https://pubmed.ncbi.nlm.nih.gov/11719309/ Accessed on 23/9/2021
  5. Veasey SC, Guilleminault C, Strohl KP, Sanders MH, Ballard RD, Magalang UJ. Medical therapy for obstructive sleep apnea: a review by the Medical Therapy for Obstructive Sleep Apnea Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine. Sleep. 2006 Aug;29(8):1036-44. doi: 10.1093/sleep/29.8.1036. PMID: 16944672.https://pubmed.ncbi.nlm.nih.gov/16944672/ Accessed on 23/9/2021
  6. Rosenberg R, Doghramji P. Optimal treatment of obstructive sleep apnea and excessive sleepiness. Adv Ther. 2009 Mar;26(3):295-312. doi: 10.1007/s12325-009-0016-7. Epub 2009 Apr 3. PMID: 19337706. https://pubmed.ncbi.nlm.nih.gov/19337706/ Accessed on 24/9/2021

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