Acne is a common skin condition. In the UK, more than 3.5 million visits are made by patients to GP practices, who seek the treatment for this condition. The first-line treatment for acne includes topical preparations, such as topical retinoid products, topical antibiotics, alone or in combination with benzoyl peroxide (NICE, 2018). Hormonal treatment is recommended when patients do not respond to first-line therapy and as an optional treatment to systemic (oral) antibiotics. Today, I review the use of Dianette for acne treatment, a hormonal (contraceptive) pill available as a prescription-only medication.