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Topamax For Weight Loss: Should I Take It Or Not?

Topamax A Good Or A Bad Alternative For Weight Loss

Everyone loves to stay fit and fine, but weight gain is a common problem every person struggles with. WHO has stated that more than 1.9 billion adults 18 years and older are overweight. Moreover, 650 million are obese.

Being overweight can create many health problems. Fortunately, the proper lifestyle and also medications can help you address obesity. It is always more beneficial to work hard physically and lose weight naturally.

Medication cannot always be beneficial to us. Topamax is one such weight loss medicine. If you have tried all possible options and are still struggling to lose weight, then Topamax can lend a helping hand to you. Let us find out how beneficial Topamax is in weight loss. Read on to know if Topamax will give you satisfactory results.

Topamax is the brand name of a generic medication known as “Topiramate”. It belongs to the drug class “anticonvulsant”. Topamax is used to prevent migraine headaches and epilepsy(seizures).

It is also used with other medications to treat seizures like Lennox-Gastaut Syndrome (LGS), partial-onset seizures, and tonic-clonic seizures. Topamax treats nerve pain, bipolar disorder, etc. too.

How Is Topamax Associated With Weight?

Topamax is not a prescription drug for weight loss. Let us find out how Topamax and weight are interconnected.

  • Studies show that you will experience loss of appetite or suppression of hunger by taking Topamax.
  • Topamax reduces the amount of a hormone called Leptin in our body. Leptin regulates appetite. When it is low, it can cause you to feel less hungry.
  • Topamax induces Ketosis. Ketosis will bring down your appetite.
  • Topamax may cause dizziness and disorientation, which will lead you to skip meals.
  • Topamax may boost your body’s metabolism. Topamax burns calories more quickly, which leads to weight loss.
  • Topamax may affect your taste by reducing saliva production. Loss of taste may result in poor eating.

Once you lose appetite and eat less, weight loss is very likely.

Does Topamax Cause Weight Loss?

Yes, Topamax causes weight loss. About 6% to 17% of people consumed Topamax for an extended period leading to significant weight loss. Children and adults both lost weight. Weight loss occurred over three to six months of treatment.

Topamax causes weight loss but the period within which weight loss takes place varies from person to person. For some, weight loss may occur within a month, whereas it can take up to four months for others.

If you experience weight loss at a swift pace, it is essential to consult your healthcare provider to assess the benefits versus risks.

First Study

As per Ehealthme, accidental weight loss was found among women aged 50-59 years who consumed Topamax for 1 to 6 months. 4.14% of women lost weight accidentally.

Second Study

As per a second study by Ehealthme, intentional weight loss was seen in women in the age group of 40-49 years old who have been consuming Topamax for more than ten years. Only 0.6% of women have lost weight intentionally.

Is It Good To Take Topamax For Weight Loss?

Who does not want a healthy body with suitable height and weight? A deviation from this, especially if you are gaining weight, can worry you. Weight once gained does not go down quickly despite following the best health practices.

In such situations, medications like Topamax can be beneficial if you want to lose weight. Weight-loss pills are like double-edged swords. It would help if you were careful when you consume them.

But it can also cause serious side effects. So be careful while consuming any medication for weight loss. Weight loss medication is never a good substitute for a healthy lifestyle.

If your BMI (Body Mass Index) is higher than 30, you are overweight or obese. You can consider medication to lose weight.

Topamax can help you lose around 11 pounds which are 5 kg. The effectiveness of Topamax depends upon the length of treatment and dosage.

Who Cannot Take Topamax For Weight Loss?

Topamax is helpful for weight loss, but it is not safe for everyone. Few people should avoid using Topamax because there is a risk of adverse effects. If you have any of the following conditions, avoid Topamax:

  • Kidney and liver disease
  • Lung disease or breathing problems
  • Heart disorders
  • Eye problems
  • Mental illnesses like depression and anxiety
  • Suicidal thoughts or behaviours
  • Osteoporosis (porous bone or disease that weakens bone)
  • Metabolic ketoacidosis (occurs in diabetic patients)
  • Pregnancy and breastfeeding infants
  • Children below 18 years of age

Side Effects Of Topamax

Common side effects of Topamax are:

  • Dizziness
  • Weakness
  • Fatigue
  • Lack of energy
  • Loss of sensation in body parts
  • Diarrhoea
  • Lack of concentration
  • Loss of coordination
  • Burning sensation

Serious side effects of Topamax are:

  • You may notice some memory problems like confusion and trouble speaking.
  • Topamax may also cause mental disorders like depression, panic attacks, mood changes, and suicidal thoughts or behaviours.
  • Rare side effects of Topamax may cause eye problems which lead to vision changes or blindness.

How To Take Topamax To Lose Weight?

Topamax comes in two forms, tablets and sprinkles capsules. You can take one dose of Topamax tablet once a day in the morning with or without food. It would help if you took Topamax at the same time every day for the best results.

Do not chew or crush the tablet. Swallow it as a whole. Drink plenty of water every day while taking Topamax to avoid dehydration and kidney problems.

Your doctor will suggest you follow a diet plan and regular exercise while consuming Topamax for weight loss. If you did not notice weight loss within 12 weeks of treatment, your doctor might switch you to a better alternative.

Limit the usage of Topamax as it is habit-forming.

How Much Is Topamax Required For Weight Loss?

Topamax dosage varies from person to person. Depending on age, weight, medical condition, length and response to treatment.

The initial dose of Topamax for weight loss is 25mg per day. Dosage should be increased gradually by observing your response to treatment.

Topamax Weight Loss Study Based On Various Conditions

Type2 Diabetes

Obesity is a common problem in many countries. In the USA, it is estimated that 22.5% of adults under 20 years old are suffering from obesity.

The study was conducted on 69 patients from the age group of 18-75, in whom 21 males and 48 females were under observation. They made two groups of people: 39 patients consumed Topamax, and 30 took another drug.

People with Type2 diabetes have noticed 5% weight loss by taking Topamax 150 mg a day. Thus Topamax was more effective than other drugs for weight loss.

  • Migraines

Another study conducted on 175 migraine patients around 41 years old consumed Topamax for headache migraine for around three months and noticed weight loss.

  • Epilepsy

A study was conducted on 49 adults consuming Topamax for around one year to treat epilepsy, and they noticed a decline in their body mass. The patients saw weight loss within three months.

Self-Health Tips To Lose Weight

Diet plays a significant role in maintaining a healthy lifestyle. You should avoid eating food that is high in calories, fats, sugar, and salt. Focus on eating fresh fruits and vegetables, which give sufficient nutrients to our body.

It would help if you exercised as it helps to control your weight. You should meditate and do physical exercise, which boosts your energy level and makes you feel happier. Overall, exercise is the safest medication for our body as it does not harm us.

If you feel stressed and depressed, it can lead to emotional eating and gaining weight. You should talk with your loved ones or perform activities that provide enjoyment and relief in such situations.

Sleep is essential to keep your body and mind in good condition. Lack of sleep may increase appetite. Daily exercise helps you to get enough peaceful sleep and also reduces stress.

You should consult a doctor and can also try safe pills and supplements to lose weight. But remember, medication is not a substitute for a healthy lifestyle, so you should always try to do physical exercise and follow a good diet plan.


Topamax is a prescribed medication used to treat migraines and various seizures. As Topamax causes weight loss, it is prescribed off-label for weight loss.

Do not consume Topamax on your own. An excessive weight loss on Topamax can lead to health complications.

Overall, Topamax works for weight loss. You need to monitor your weight and severe side effects, if any, closely.

It is essential to supplement Topamax with a healthy lifestyle and diet plan. Topamax is not a shortcut to weight loss.

Can I take Topamax with alcohol?
You should avoid consuming alcohol 6 hours before or 6 hours after taking a Topamax dose because combining the two can have an additive effect.
Does Topamax cause hair loss?
Hair loss is a mild side effect of Topamax. It occurs in people who consume Topamax to treat epilepsy (seizures) and prevent migraine headaches.
How long does Topamax take to stay in your system?
It may depend on personal factors like age, weight, dosage, medical condition and what other medication you are taking currently. Topamax stays in your system for 4 to 5 days after the last dose.
Does Topamax treat anxiety?
Topamax has not been approved to treat anxiety. Still, after consuming Topamax, you may feel sleepy, and Topamax can be prescribed off-label in people to treat anxiety disorders like obsessive-compulsive disorder (OCD).